CRISPR/dCas9-targeted H3K27me3 demethylation at the CUC3 boundary gene triggers ectopic transcription and impacts plant development

Summary: Chromatin modifications are deemed to correlate with gene expression patterns, yet their direct causal effect on transcription and cell fate remains unestablished.The H3K27me3 modification, highly conserved in eukaryotes, is strongly associated with the repression of developmental genes.Here, we establish the genuine function of H3K27me3 i

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Stabilising Springs for Fixed Lingual Retainer

Most treated malocclusion needs fixed lingual retention.To stabilise fixed lingual Finger Cots retainer in the exact location needs proper stabilisation.Proper stabilization requires a holding spring.This Stabilising Spring should be easy to fabricate and help the clinician to stabilise the retainer quickly and save the chair side time.More over it

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